FSnet Sept. 14/06 -- III

Fresh and risky

Dole sued by Oregon E. coli victim

FDA warning on serious foodborne E.coli O157:H7 outbreak: One death and multiple hospitalizations in several States

Feds warn: Don't eat fresh bagged spinach: One dead, 50 sickened in nine states, including Ore.

Three ill as E.coli hits nursery

Three confirmed Salmonella cases in Polk

Food safety under chief's microscope

Four outbreaks of norovirus gastroenteritis after consuming raspberries, Sweden, June-August 2006

Advisory - Health Canada advises against use of the Ayurvedic medicinal product Jambrulin due to lead content

Appliance of science

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Fresh and risky
14.09.06
Commentary from the Food Safety Network
Douglas Powell and Ben Chapman
www.foodsafety.ksu.edu
Now it's killer spinach.
The U.S. Food and Drug Administration (FDA) announced this evening that, based on preliminary epidemiological evidence, bagged fresh spinach may be the common food in an outbreak of E. coli O157:H7 that has left one person dead and at least 50 others sick in eight states. Of those, 8 individuals have developed a form of kidney failure called hemolytic uremic syndrome. FDA is telling consumers to not eat bagged fresh spinach at this time.
This is going to be a major outbreak, and not just because of the pain and suffering, the business losses, the increased consumer skepticism.
For the industry, the timing is terrible, following a nationwide warning to consumers in early October 2005 against eating certain pre-packaged Dole salad products because the lettuce had been associated with an outbreak of E. coli O157:H7 in Minnesota in which at least 18 people fell ill, further ratcheting up attention on the $2 billion lettuce (and spinach) industry.
And maybe that's a good thing.
On Nov. 4, 2005, Dr. Robert Brackett, director of FDA's Center for Food Safety and Applied Nutrition, wrote California lettuce producers, packers and shippers, urging them to re-examine and modify operations from the farm through to distributors to ensure that consumers were provided with a safe product.
Dr. Brackett's November letter noted that FDA was aware of 18 outbreaks of foodborne illness since 1995 caused by E. coli O157:H7 for which fresh or fresh-cut lettuce was implicated as the outbreak vehicle. In one additional case, fresh-cut spinach was implicated. These 19 outbreaks accounted for 409 reported cases of illness and two deaths.
A subsequent Dateline NBC report on the Dole outbreak spawned a summer of Internet-amplified warnings about the perils of bagged lettuce, many of them false, which will now, with the latest outbreak, be recycled as truth.
And last week, FDA officials were in California's Salinas Valley -- the "Salad Bowl of the World," -- promising increased scrutiny on the industry.
Fresh fruits and vegetables are good for us; we should eat more. Yet fresh fruits and vegetables are one of, if not the most, significant source of foodborne illness today in North America. With an estimated 76 million illness and 5,000 deaths in the U.S. each and every year from foodborne illness, that's just too much.
The problem with fresh produce is that the very characteristic that affords dietary benefit -- fresh -- also affords microbiological risk.
Because they are not cooked, anything that comes into contact with fresh fruits and vegetables is a possible source of contamination. Is the water used for irrigation or rinsing clean or is it loaded with pathogens? Do the workers who collect the produce follow strict hygienic practices such as thorough handwashing? What happens to that head of lettuce once it gets on to the sorting line, and then gets chopped up? The possibilities are almost endless.
Even more challenging is that many of these problems must be controlled on the farm. There are situations where the most ardent washing of produce by consumers will accomplish … nothing; in some cases, the dangerous bugs can actually reside within the fresh produce.
Instead of the banal -- and in this case, entirely ineffective -- advice to thoroughly wash all produce, consumers, restaurants, grocery stores, everyone, should be asking some difficult but basic questions: what do growers of fresh lettuce or spinach do to control dangerous microorganisms like E. coli O157:H7?
The U.S. lettuce/leafy greens industry took the first step in doing this, releasing a comprehensive set of food safety guidelines, from the farm through to retail, in April, 2006. That's nine years after the FDA first drew attention to the problem of fresh produce. And even though grower groups will tomorrow say, "We have these guidelines …" that is not nearly good enough.
For the past decade, numerous on-farm programs have been created and touted, yet outbreaks associated with produce continue unabated.
Programs mean manuals, checklists and bureaucratic oversight. What's needed is the data to illustrate where, why and how dangerous bugs get into fresh produce, and, equally important, people to provide on-going interaction with farmers, retailers and food service, to compel each individual in the farm-to-fork food safety system to do whatever is possible to further enhance the safety of fresh produce.
We have worked with growers of fresh produce for the past 10 years, and know that any grower can clean up for a once-a-year audit. Given the on-going outbreaks, growers that want to stay in business, will get some food safety religion for the other 364 days of the year.
Seattle food safety attorney William Marler, who this evening filed a lawsuit in the spinach outbreak, recently noted, "Consumers cannot be left as the last line of defense. Adulterated lettuce (or spinach) should not be making it into the hands of consumers – or retailers, for that matter – in the first place."
Dr. Douglas Powell is scientific director of the Food Safety Network at Kansas State University and Ben Chapman is a PhD student at the University of Guelph. They are the authors of, most recently, an academic book chapter entitled, Implementing On-Farm Food Safety Programs in Fruit and Vegetable Cultivation, in the recently published, Improving the Safety of Fresh Fruit and Vegetables
http://www.woodheadpublishing.com/en/book.aspx?bookID=831
dpowell@ksu.edu



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Dole sued by Oregon E. coli victim
14.sep.06
Marler Clark
http://www.marlerclark.com/news/dole-spinach-ecoli.htm
PORTLAND, OR – An E. coli lawsuit was filed against Dole late Thursday in United States District Court for the District of Oregon. The lawsuit was filed on behalf of Gwyn Wellborn, a Salem, Oregon woman who became ill with an E. coli O157:H7 infection after eating Dole brand baby spinach. Ms. Wellborn and her husband, David, are represented by Marler Clark, the Seattle law firm that has represented hundreds of victims E. coli outbreaks, including victims of last fall’s E. coli outbreak traced to Dole brand lettuce.
The lawsuit alleges that Mrs. Wellborn purchased Dole brand baby spinach on August 21, 2006 and consumed the spinach in salads over several days during the week of August 21 through August 25. Ms. Wellborn became ill with symptoms of E. coli O157:H7 infection, including diarrhea and stomach cramping, on August 25. Her symptoms continued to worsen, and Mr. Wellborn took his wife to the emergency room at Salem Hospital in the early morning hours of August 27. Ms. Wellborn was treated and released, but was admitted to Salem Hospital after a second visit to the emergency room at midday on the 27th. She remained hospitalized at Salem Hospital for six days, and was transferred to Oregon Health Sciences University (OHSU) in Portland on September 2 after being diagnosed with hemolytic uremic syndrome (HUS).* While at OHSU, Ms. Wellborn required at least four blood transfusions and eight plasmapheresis exchanges. She was discharged from OHSU on September 8, and continues her recovery at home.
“The FDA and the fresh produce industry have been working to resolve the issue of E. coli contamination for a number of years,” said William Marler, attorney for the Wellborns. “It is unfortunate that outbreaks continue to happen and that consumers continue to be injured as a result.”
BACKGROUND: Marler Clark has extensive experience representing victims of foodborne illnesses. William Marler represented Brianne Kiner in her $15.6 million settlement with Jack in the Box in 1993. In 1998, Marler Clark resolved Odwalla Juice E. coli outbreak cases for five families whose children developed HUS and were severely injured after consuming contaminated apple juice for a reported $12 million. Mr. Marler recently resolved an HUS case for $11 million.
Hemolytic uremic syndrome is a frightening illness that even in the best American medical facilities has a mortality rate of about 5%. About 50% of patients require dialysis due to kidney failure, 25% experience seizures, and 5% suffer from diabetes mellitus. The majority of HUS patients requires transfusion of blood products and develops complications common to the critically ill. Among survivors of HUS, about five percent will eventually develop end stage kidney disease, with the resultant need for dialysis or transplantation, and another five to ten percent experience neurological or pancreatic problems which significantly impair quality of life.



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FDA warning on serious foodborne E.coli O157:H7 outbreak: One death and multiple hospitalizations in several States
14.sep.06
U.S FDA Press Release
The U.S. Food and DrugAdministration (FDA) is issuing an alert to consumers about an outbreak of E. coli O157:H7 in multiple states that may be associated with the consumption of produce. To date, preliminary epidemiological evidence suggests that bagged fresh spinach may be a possible cause of this outbreak.
Based on the current information, FDA advises that consumers not eat bagged fresh spinach at this time. Individuals who believe they may have experienced symptoms of illness after consuming bagged spinach are urged to contact their health care provider.
"Given the severity of this illness and the seriousness of the outbreak, FDA believes that a warning to consumers is needed. We are working closely with the U.S. Centers for Disease Control and Prevention (CDC) and state and local agencies to determine the cause and scope of the problem," said Dr. Robert Brackett, Director of FDA's Center for Food Safety and Applied Nutrition (CFSAN). E. coli O157:H7 causes diarrhea, often with bloody stools. Although most healthy adults can recover completely within a week, some people can develop a form of kidney failure called Hemolytic Uremic Syndrome (HUS). HUS is most likely to occur in young children and the elderly. The condition can lead to serious kidney damage and even death. To date, 50 cases of illness have been reported to the Centers for Disease Control and Prevention, including 8 cases of HUS and one death. At this time, the investigation is ongoing and states that have reported illnesses to date include: Connecticut, Idaho, Indiana, Michigan, New Mexico, Oregon, Utah and Wisconsin.
FDA will keep consumers informed of the investigation as more information becomes available.



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Feds warn: Don't eat fresh bagged spinach: One dead, 50 sickened in nine states, including Ore.
14.sep.06
The Associated Press and KTVZ.com news sources
http://www.ktvz.com/story.cfm?nav=news&storyID=16636
Federal health officials are warning people not to eat bagged fresh spinach after an outbreak of E. coli in eight states, including Oregon, has left at least one person dead and 50 others sick.
The death occurred in Wisconsin. The cases of people getting sick were reported in Connecticut, Idaho, Indiana, Michigan, New Mexico, Oregon and Utah.
Epidemiologists in the Oregon Department of Human Services and in Wisconsin have traced the illness to packaged, washed spinach, although they so far have been unable to identify whether the contamination is confined to a single brand.
DHS epidemiologist Bill Keene was quoted as saying Thursday afternoon, "We have reports of cases of E. coli O157 illness in Oregon, Idaho, Washington,
Wisconsin, Utah, New Mexico, Connecticut, Indiana and Michigan. Although we have identified packaged spinach as the source, people have either varying or no recollection of the brand they purchased."
Keene said that epidemiologists are asking people who have become ill for credit and cash-register receipts they received when they made the purchase. "We're now trying to pin down the brand," he said. Although five persons' illness has been confirmed by the state public health laboratory, he said, state epidemiologists have received reports of illness in several dozen people and are working with them as well.
Keene said DHS would name the brand of the contaminated product publicly as soon as it is identified.



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Three ill as E.coli hits nursery
14.sep.06
BBC News
A two-year-old child has become the second suspected case of E.coli from a Brighton nursery since it was closed following an outbreak of the bacterium.
The Hilltop Nursery was closed on Friday after a three-year-old caught the infection and an 18-month-old was treated for a suspected case.
The three-year-old is being treated in hospital. Those suspected of having E.coli are being cared for at home.
A spokeswoman said the nursery would reopen when it was clear of the bug.
The nursery caters for children of NHS staff working at Brighton General Hospital and is on the hospital site.



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Three confirmed Salmonella cases in Polk
14.sep.06
Tryon Daily Bulletin (N.C.)
Leah Justice
http://www.tryondailybulletin.com/news/19618.asp
The Rutherford-Polk-McDowell District Health Department has confirmed three Salmonella cases in Polk County recently.
Helen White, RN, PHN Supervisor at Rutherford-Polk-McDowell District Health Department, was cited as saying all three cases involve Polk County High School students but no connection among them has yet been established. Officials are still in the surveying stage, she said, and have not yet determined where Salmonella was contracted or if the cases are related.
More cases of Salmonella are possible as other students have reported experiencing similar symptoms without going to a physician.
White says the health department has worked well with the N.C. Department of Health and Human Services and the Polk County School system to test and monitor students. Officials asked students what and where they ate as far back as 72 hours prior to developing symptoms.
White says these are the first confirmed cases of Salmonella this year, and the number and timing of the cases seems to follow a pattern that has developed in Polk County over the past several years.



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Food safety under chief's microscope
14.sep.06
The Standard
Caroline Kim
Chinese University of Hong Kong microbiologist Kwan Hoi-shan, who has been appointed chairman of the newly formed Expert Committee on Food Safety, was cited as saying Thursday the panel aims to educate the public on "accurate and appropriate food handling and proper hygiene" and that a recent spate of food poisoning cases was due to a lack of awareness by the public.
His committee will also look at standards in food handling as well as the technological advancements in packaging and processing which may be of help to restaurants.
However, Kwan would not directly comment on the 22 cases of food poisoning in Ma On Shan which resulted in a restaurant being closed, or the 10 cases in Sham Shui Po just four days ago.



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Four outbreaks of norovirus gastroenteritis after consuming raspberries, Sweden, June-August 2006
14.sep.06
Eurosurveillance Weekly
M Hjertqvist1 (marika.hjertqvist@smi.ki.se), A Johansson2, N Svensson2, PE Åbom3, C Magnusson 4, M Olsson2, KO Hedlund1, Y Andersson1
1Swedish Institute for Infectious Disease Control, Stockholm, Sweden
2Department of Communicable Disease Control, Västra Götaland, Sweden
3Department of Communicable Disease Control, Jönköping, Sweden
4Municipality of Gnosjö, Sweden
So far in 2006, in Sweden, there have been four outbreaks of norovirus gastroenteritis where raspberries were the suspected vehicle of infection. The first outbreak occurred at the end of June, the second was at the beginning of August and the third and fourth at the end of August. All the outbreaks occurred in the south western part of the country. In total, 43 people became ill and all these people had eaten raspberries as part of various different dishes.
Outbreak 1
On 23 June, a group of 15 people met at a private party, where they ate homemade cake containing cream and raspberries. One or two days after, 12 people fell ill with gastrointestinal symptoms. Stool samples from two patients were tested and found positive for norovirus by PCR.
Outbreak 2
On 2 August, there was a family gathering of 11 people on the west coast of Sweden. Cheesecake with raspberries was served at the party and was eaten by all of the guests. The following day, 10 people fell ill with signs and symptoms typical of norovirus infection. Later, two secondary cases were reported. No faecal samples were taken, as the patients had already recovered by the time the outbreak was notified to the authorities. During the outbreak investigation it was determined that the raspberries in the cheesecake were of the same brand as in the first outbreak and imported from China.
Outbreak 3
On 24 August a school class with about 30 pupils aged 13 prepared drinks with raspberries. A mother of one of the children reported that her child had become ill on 26 or 27 August. The county medical officer carried out a cohort study and it was discovered that 12 children had been ill. The incubation period was 24-36 hours, the symptoms vomiting, fever, diarrhoea and headache. The duration of disease was 1-3 days. Faecal samples from two children tested positive for norovirus by PCR. Leftovers of raspberries in a plastic bag were saved for later analysis. These raspberries were the same brand as the other outbreaks.
Outbreak 4
On 25 August, a meeting took place with nine participants. The guests ate baguettes with filling from a catering company and a homemade raspberry parfait for dessert. Following this meeting, all nine people fell ill. One stool sample was taken for testing, and this was positive for norovirus. Raspberries were left over and saved for testing – results are pending. These berries were also the same brand as in the previous outbreaks.
Conclusion
All of the suspected raspberries in these outbreaks were the same brand, and from the same distributor in Sweden who imported these from China. Raspberries were left over in two outbreaks and results of further tests on the raspberries are pending. On 23 August two batches of raspberries, were withdrawn from the market.
Outbreaks of gastroenteritis caused by norovirus from frozen imported raspberries have been reported from several European countries in recent years [1,2,3]. Since 2000 in Sweden, there have been 11 outbreaks of gastroenteritis caused by norovirus where the suspected food has contained raspberries (database at Smittkyddsinstitutet).
References:
1. Falkenhorst G, Krusell L, Lisby M, Madsen S, Böttiger B, Mølbak K. Imported frozen raspberries cause a series of norovirus outbreaks in Denmark, 2005. Euro Surveill 2005;10(9):E050922.2. (http://www.eurosurveillance.org/ew/2005/050922.asp#2)
2. Cotterelle B, Drougard C, Rolland J, Becamel M, Boudon M, Pinede S, Traoré O, Balay K, Pothier P, Espié E. Outbreak of norovirus infection associated with the consumption of frozen raspberries, France, March 2005. Euro Surveill 2005;10(4):E050428.1. (http://www.eurosurveillance.org/ew/2005/050428.asp#1)
3. Pönkä A, Maunula L, von Bonsdorff CH, Lyytikäinen O. Outbreak oof calicivirus gastroenteritis associated with eating frozen raspberries. Euro Surveill 1999; 4(6): 66-69 (http://www.eurosurveillance.org/em/v04n06/0406-222.asp)



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Advisory - Health Canada advises against use of the Ayurvedic medicinal product Jambrulin due to lead content
14.sep.06
from a press release
OTTAWA - Health Canada is advising consumers not to use the Ayurvedic medicinal product Jambrulin because it contains high levels of lead. Consumption of heavy metals such as lead can pose serious health risks because they may accumulate in the body's vital organs. Infants, children and pregnant women are most susceptible to the toxic effects of lead. Ingesting lead can affect nearly every organ and system in the human body and can cause abdominal pain, anaemia, changes in blood pressure, negative reproductive effects, weakness, concentration problems, weight loss, insomnia, dizziness, kidney and brain damage, and can lead to death. Jambrulin is manufactured by Unjha Pharmacy in India and comes in tablet form. Its packaging states that the product can be used to activate the pancreas.
Ayurvedic medicinal products are used in traditional Indian healing practice and are often imported from India. According to the principles of Ayurvedic medicine, heavy metals may be used in a detoxified state in these products because of their reputed therapeutic properties. However, improper manufacturing processes may result in dangerously high levels of heavy metals in the final product.
Jambrulin is not authorized for sale in Canada and has not been found on the Canadian market. However, it is available for sale over the Internet. It may also have been brought into the country for personal use by travellers. Health products that have been assessed by Health Canada for safety, efficacy and quality will either bear an eight-digit Drug Identification Number (DIN), a Natural Product Number (NPN), or a Homeopathic Drug Number (DIN-HM). Consumers who have used this product and who are concerned about their health should contact a health professional for advice. For more information about lead poisoning, contact the nearest poison control centre. Its number should be in the first pages of your local phone book. You can also look at the It's Your Health (http://www.hc-sc.gc.ca/iyh-vsv/environ/lead-plomb_e.html) fact sheet on the effects of lead on human health.
Health Canada issued public advisories in June 2006 and March 2005 and a public warning in July 2005 about the risk of heavy metal toxicity associated with other Ayurvedic medicinal products.
Some Ayurvedic medicinal products contain high levels of heavy metals (http://hc-sc.gc.ca/ahc-asc/media/advisories-avis/2006/2006_46_e.html) Some Ayurvedic medicinal products reported to contain high levels of heavy metals (http://hc-sc.gc.ca/ahc-asc/media/advisories-avis/2005/2005_09_e.html) Health Canada warns consumers not to use certain Ayurvedic medicinal products (http://hc-sc.gc.ca/ahc-asc/media/advisories-avis/2005/2005_80_e.html) Consumers who find any of the products listed in these advisories on the Canadian market are asked to contact the Health Products and Food Branch Inspectorate at 1-800-267-9675.
No adverse reactions associated with Jambrulin have been reported to Health Canada.
Consumers requiring more information about this advisory can contact the Health Canada public inquiries line at (613) 957-2991, or toll free at 1-866-225-0709.
To report a suspected adverse reaction to this or any other health
product, please contact the Canadian Adverse Drug Reaction Monitoring Program
(CADRMP) of Health Canada by one of the following methods:
Telephone: 1-866-234-2345
Facsimile: 1-866-678-6789
CADRMP
Marketed Health Products Directorate
Tunney's Pasture, AL 0701C
Email: cadrmp@hc-sc.gc.ca
The CADRMP adverse reaction reporting form, including a version that can be completed and submitted online, is located on the MedEffect portal (www.medeffect.gc.ca) of the Health Canada Web site.



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Appliance of science
14.sep.06
Food Standards Agency (UK)
Food Standards Agency (UK)
http://www.foodstandards.gov.uk/news/newsarchive/2006/sep/applianceof
The Food Standards Agency today launched a recruitment campaign for Scientific Officers based at its London offices.
The new intake of scientists will work in business areas such as nutrition, chemical safety, food hygiene and enforcement.
Candidates must possess a degree in a science subject and excellent communication and interpersonal skills. They must be proactive and be able to manage deadlines and prioritise tasks. In addition, they need to grasp scientific data and demonstrate problem solving ability.
How to apply
Candidates complete an application form. Those applicants whose skills and qualifications most closely match requirements will be invited to an assessment day. A written test, personal presentation, group exercise and interviews then help identify the strongest candidates.
For an application pack, please call 0845 601 3384, email fsa.so@adecco.co.uk or visit www.scientific-officers.co.uk
The closing date for completed application forms is 4pm, 5 October 2006.
Science
The Food Standards Agency aims to be trusted as the UK’s most reliable source of advice and information about food. Priorities include:
Reducing foodborne illnesses by 20% by improving food safety throughout the food chain
Improving enforcement of food law
Protecting consumers through improved safety and standards
Access to reliable evidence is key to achieving these goals, so the work of scientists is integral to what the Agency does and says.
Subscribe
You can now subscribe to receive email alerts for job vacancies in the Agency. Choose from scientific, specialist, or administrative vacancies, or, to receive alerts for all advertised posts subscribe for all three.
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