ANIMALNET MAY 20

ANIMALNET MAY 20, 2003 -- II

Guidance on mass spectrometry for confirmation of animal drug residues
available
Newcastle disease, game fowl, poultry -- USA (West) (15)
Media missives about meat industry
Iowa State University hosts manure management sessions
Reminder to scientists involved in research with genetically engineered
animals
Put a turkey in your tank

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GUIDANCE ON MASS SPECTROMETRY FOR CONFIRMATION OF ANIMAL
DRUG RESIDUES AVAILABLE
May 19, 2003
Center for Veterinary Medicine
http://www.fda.gov/cvm/index/updates/GL118up.htm
The Food and Drug Administration (FDA) is announcing the availability of
³Guidance For Industry: Mass Spectrometry for Confirmation of the Identity
of Animal Drug Residues² (Guidance #118.) Final Guidance #118 elaborates the
description of method specificity in Center for Veterinary Medicine (CVM)
Guidance Document 3, ³General Principles for Evaluating the Safety of
Compounds Used in Food Producing Animals,² Part V, Guideline for Approval of
a Method of Analysis for Residues, section B.1 The aim of Guidance Document
#118 is to facilitate the development, review, and testing of methods
submitted to CVM. Where it can be predicted that using a new animal drug in
food animals will likely result in the presence of drug residues in the
edible tissue of a treated animal, a full confirmatory procedure should be
developed and validated. The Guidance includes specific recommendations on
method development and validation, method description, confirmation criteria
for a range of data acquisition techniques, and quality control. For cases
when a full procedure is unavailable and time does not permit a procedure to
be fully validated, an ad hoc confirmatory package may be assembled.
Guidance Document #118 is posted on the FDA/Center for Veterinary Medicine
Home Page . Single copies of the guidance may be obtained by writing to the
Communications Staff, FDA/Center for Veterinary Medicine, 7519 Standish
Place, HFV-12, Rockville, MD 20855. Please send a self-addressed adhesive
label to assist in processing your request. Written or electronic comments
on Agency guidance documents may be submitted at any time to the Dockets
Management Branch (HFA-305), Food and Drug Administration, 5630 Fishers
Lane, Room 1061, Rockville, MD 20852. Comments should be identified with the
full title of the guidance document and Docket number 01D-0224. Electronic
comments may be submitted to http://www.fda.gov/dockets/ecomments. Once on
this site, select ³Docket number 01D-0224, Guidance for Industry: Mass
Spectrometry for Confirmation of the Identity of Animal Drug Residues.²
Additional information about the guidance document may be found in the May
13, 2003, Federal Register and from David N. Heller, Center for Veterinary
Medicine (HFV-510), Food and Drug Administration, 8401 Muirkirk Rd., Laurel,
MD 20708, 301-827-8156, e-mail:
dheller@cvm.fda.gov

NEWCASTLE DISEASE, GAME FOWL, POULTRY -- USA (WEST) (15)
May 19, 2003
A ProMED-mail post
http://www.promedmail.org
ProMED-mail, a program of the
International Society for Infectious Diseases
http://www.isid.org
Thomas E Walton
Source: Official APHIS release
Subject: Emergency Management Warning 93: Exotic Newcastle Disease
Confirmed in the United States
Exotic Newcastle disease (END) was confirmed on 1 Oct 2002 in the State of
California and has now spread beyond backyard flocks to affect 22 commercial
operations in California. On 16 Jan 2003, END was also confirmed in a
backyard flock in the State of Nevada. A backyard flock was confirmed with
END on 4 Feb 2003, in the State of Arizona. On 9 Apr 2003, END was also in
backyard fowl in Texas. Clinical signs in infected birds include
respiratory, nervous, and gastrointestinal signs. Mortality is up to 90
percent of exposed birds.
Investigations are ongoing, and all figures are pending final validation.
Animal and Plant Health Inspection Service (APHIS) personnel and other
federal government personnel are working with the States to consider
additional resources to meet the labor demands at the Task Forces. APHIS
has implemented a plan for enhanced national END surveillance.
Current Statistics
Operations in Progress
Current Statistics: California / Texas / Total
Personnel Assigned: 1063 / 31 / 1094
Premises Currently Quarantined: 14 928 / 476 / 15 404
Current Positive Premises:
CA: 354 backyard, 17 commercial
TX: 1 backyard,       0 commercial
Total: 355 backyard, 17 commercial
Current Contact Premises:
CA: 316 backyard, 1 commercial
TX: 0 backyard, 0 commercial
Total: 316 backyard, 1 commercial
Premises Pending Depopulation: 10 / 0 / 10
Cumulative Statistics: California / Texas / Total Total Premises
Quarantined: 17 405 / 496/ 17 901 Total Premises Released: 2456 / 1 / 2457
Total Positive Premises:
CA: 895 backyard (+1), 21 commercial (no change)
TX: 1 backyard (no change), 0 commercial (no change)
Total: 896 backyard (+1), 21 commercial (no change)
Total Premises Depopulated: 2430 (no change) / 41 (no change) / 2471 (no
change)
Total Birds Depopulated:       3 492 568 (no change) / 1823 (no change) / 3
494 391 (no change)
Counties with Currently Positive and/or Contact Premises: Kern, Los
Angeles, Riverside, San Bernardino, San Diego, Ventura, El Paso
Completed Operations (Final Numbers): Arizona / Nevada / Total
Total Infected Premises: 1 / 10 / 11
Total Contact Premises: 3 / 10 / 13
Total Premises Quarantined: 1 / 0 / 1
Total Premises Released: 66 / 155 / 221
Total Premises Depopulated: 6 / 147 / 153
Total Birds Depopulated: 269 / 2746 / 3015
Last Infected Premises Depopulated: 7 Feb 2003 / 29 Jan 03
Operational Update
  ----------------
Effective 7 Jan 2003, APHIS imposed a federal quarantine that regulates the
interstate movement of all species of birds and poultry products from
Imperial, Los Angeles, Orange, Riverside, San Bernardino, San Diego, Santa
Barbara, and Ventura Counties, CA.
Effective 17 Jan 2003, APHIS imposed a federal quarantine that regulates the
interstate movement of all species of birds and poultry products from Clark
and a portion of Nye County, NV.
Effective 10 Feb 2003, APHIS imposed a federal quarantine that regulates the
interstate movement of all species of birds and poultry products from all of
La Paz and Yuma Counties and a portion of Mohave County, AZ.
Effective 14 May 2003, Mohave and Yuma Counties, AZ, Nye County, NV, and
portions of La Paz County, AZ, and Clark County, NV, were removed from the
list of quarantined areas because of exotic Newcastle disease.
Effective 10 Apr 2003, APHIS imposed a federal quarantine that regulates
the interstate movement of all species of birds and poultry products from
all of El Paso and Hudspeth Counties, TX, and Dona Ana, Luna, and Otero
Counties, NM. The federal quarantine was placed on counties beyond the
infected county due to their proximity to the infected county. A
quarantine was placed on a portion of New Mexico because of its proximity to
the infected area in the State of Texas
Effective 14 May 2003, APHIS imposed a federal quarantine that regulates the
interstate movement of all species of birds and poultry products from a
portion of Kern County, CA.
The U.S. Department of Agriculture (USDA) has declared an extraordinary
emergency for the States of Arizona, California, Nevada, Texas, and New
Mexico. These declarations allow USDA to apply federal authority within
Arizona, California, Nevada, New Mexico, and Texas.
Currently there are still 18 commercial premises in the State of California
affected by END. The breakdown of the commercial premises involved is as
follows: 4 premises in Riverside County (3 infected and 1 contact), 5
premises in San Diego County (5 infected), and 9 premises in San Bernardino
County (9 infected).
DNA sequencing analysis confirms that the Texas END outbreak was caused by a
separate introduction of virus and not by movement of virus from the
affected areas in California, Nevada, or Arizona. Intensified surveillance
in El Paso County, TX, and the surrounding areas has yielded no further
positive cases, suggesting that our early detection and swift response has
worked well to contain and eliminate this outbreak.
Outreach Activities
  ---------------
END Task Force personnel passed out educational materials at their booth
during a Mother's Day celebration in Bakersfield, CA. The sponsor of the
celebration is a local Spanish-language radio station.
In conjunction with the Task Force, the Texas Animal Health Commission in
Austin continues to send out information packets to stakeholder
organizations; most recently, the commission has mailed materials to feed
stores, veterinary clinics, and pet stores.
The following link is to the State of California's END website.
<http://www.cdfa.ca.gov/ahfss/ah/Newcastle_info.htm
The following link is to the State of Nevada's END website.
<http://www.agri.state.nv.us/END.htm
The following link is to the State of Arizona's END website.
<http://agriculture.state.az.us/newcastle.htm
The following link is to the State of Texas' END website.
<http://www.tahc.state.tx.us/animal_health/diseases/end/end.shtml
Please forward this information to your federal, State, and industry
counterparts as necessary.
If you have any questions about this situation, please feel free to call
USDA, APHIS, VS, Emergency Programs at 800-940-6524, 301-734-8073, or e-mail
at EMOC@APHIS.USDA.GOV.
--
Thomas E. Walton
[see also:
Newcastle disease, game fowl, plty - USA(west) (14) 20030515.1212 Newcastle
disease, game fowl, plty - USA (west) (13) 20030505.1121 Newcastle disease,
game fowl, plty. - USA (west)(02) 20030211.0372 Newcastle disease, game
fowl, plty. - USA (west) 20030206.0318 Newcastle disease, poultry - USA
(TX): OIE (02) 20030425.1014 Newcastle disease, poultry - USA (TX): OIE
20030423.0987 Newcastle disease, game birds - USA (TX) (02): confirmed
20030410.0870 Newcastle disease, game birds - USA (Texas): suspect
20030407.0848 Newcastle disease, game birds, poultry - USA (CA) (06)
20030209.0353 Newcastle disease, poultry - USA: correction 20030428.1044
Newcastle disease, poultry - USA: EU import ban 20030427.1036]
........tg/pg/jw

MEDIA MISSIVES ABOUT MEAT INDUSTRY
May 19, 2003
Lean Trimmings
Edited by Kiran Kernellu
FSIS reported that the Washington State Beef Commission, Washington Dairy
Products Commission and Midway Meats, Inc., have filed a complaint with the
Washington News Council (WNC) against Seattle's KIRO-TV. The complaint
involves a series of stories aired by KIRO-TV in November 2002 that depicted
alleged inhumane handling violations at Midway. The complainants contend
that the stories were "factually inaccurate, incomplete, misleading,
sensationalized, biased" and damaging to the reputations of the complainants
as well as to that of the U.S. Department of Agriculture. USDA is not a
party to the complaint. The WNC will hold a public hearing on the matter on
June 14. The WNC is an independent, nonprofit, statewide organization that
hears complaints from readers, viewers or listeners that feel personally
damaged by news stories written or broadcast about them. The WNC is not a
government entity and has no authority to control or penalize the news
media, but does have the autho rity to publicize its findings to the state's
media.

IOWA STATE UNIVERSITY HOSTS MANURE MANAGEMENT SESSIONS
May 20, 2003
Meatingplace.com
Daniel Yovich
Livestock producers who are interested in developing manure management plans
for their operations are invited to attend a series of workshops sponsored
by Iowa State University Extension through the end of the year.
ISU Extension agricultural engineering field specialist Kris Kohl is
coordinating the series. Kohl said 29 workshops have been set in 17 counties
in northwest Iowa. All workshops are scheduled from 10 a.m. to 3 p.m.
"Producers do not need to attend a workshop in their own county," Kohl said.
"They can attend any workshop that fits their schedule, but should call the
host county office to reserve space because seating is limited to 20
people."
Plans will be developed according to the Iowa Department of Natural
Resources requirements for annual submissions. Producers should bring to the
workshop these items: aerial photographs from their county Farm Service
Agency office, plant maps, and written manure agreements and conservation
plans for highly erodible land.
The workshop fee is $25 for any site, which covers lunch and all necessary
manure plan forms. For more information and a link to a brochure with
workshop dates, locations and phone numbers, check the Iowa Pork Industry
Center Website at IaState.edu. For more information on program content,
contact Kohl at 712/732-5056.
Below is the list of counties, dates and ISU Extension county office numbers
for this workshop series:
Buena Vista - July 23, Dec. 16, 712/732-5056
Calhoun - Oct. 20, 712/297-8611
Carroll - June 25, Sept. 11, 712/792-2364
Cherokee - June 17, Sept. 3, 712/225-6196
Crawford - Aug. 21, 712/263-4697
Dickinson - June 30, 712/336-3488
Emmet - Sept. 4, 712/362-3434
Ida - May 28, Aug. 20, 712/364-3003
Kossuth - July 15, Nov. 18, 515/295-2469
Lyon - June 24, Aug. 7, 712/472-2576
Monona - July 24, 712/423-2175
O'Brien - May 22, Aug. 12, 712/757-5045
Osceola - July 9, Dec. 10,712/754-3648
Palo Alto - Aug. 13, Dec. 9, 712/852-2865
Plymouth - Sept. 15, Nov. 25, 712/546-7835
Sac - Aug. 29, Nov. 4, 712/662-7131
Sioux - July 22, Oct. 29, 712/737-4230

REMINDER TO SCIENTISTS INVOLVED IN RESEARCH WITH GENETICALLY ENGINEERED
ANIMALS
May 19, 2003
Center for Veterinary Medicine
http://www.fda.gov/cvm/index/updates/univletter.htm
The Food and Drug Administration (FDA) has sent letters to all Land Grant
universities reminding those involved in research involving genetic
engineering in animals that such research may need to be performed under the
authority of an investigational new animal drug exemption (INAD) or a
similiar provision. The INAD regulations are published in the Code of
Federal Regulations, Title 21, Part 511.1(b). As part of the INAD
submission, those conducting this type of research must document their plans
regarding the disposition of all investigational animals after their
participation in the study is completed. This is important in the case of
animal species commonly used for food.
FDA sent these letters to help prevent another situation similiar to that
one occurred recently at the University of Illinois at Champaign-Urbana. FDA
has determined that pigs involved in certain genetic engineering studies at
the University were possibly not properly not disposed of, and instead,
entered the food supply.
To date, FDA has not permitted genetically engineered animals to be placed
into the human food supply. Likewise, only in certain circumstances has the
FDA allowed animals from genetic engineering investigations to be rendered
and incorporated into animal feed. Researchers who have questions about
their responsibilities may contact John Matheson at jmatheso@cvm.fda.gov ,
(301) 827-6649, for further information. They also may want to consult the
FDA Center for Veterinary Medicine (CVM) Biotechnology Home Page at . A
copy of the letter sent to Land Grant universities is posted on this same
page.

PUT A TURKEY IN YOUR TANK
May 20, 2003
MeatNews.com
http://www.meatnews.com/index.cfm?fuseaction=Article&artNum=5417
Scientist investigates process that converts meat processing waste into
motor fuel.
A process for cooking and pressurising waste turkey parts and other products
into a golden liquid that can be refined into heating oil, diesel fuel, or
gasoline, has been developed in the USA.
Brian Appel, CEO of Changing World Technologies has attracted the attention
of former CIA Director James Woolsey, who says the process can reduce US
dependence on foreign oil. Mr Woolsey is an advisor to Changing World.
Mr Appel's process, called thermal depolymerisation, is essentially an
accelerated version of ''the oldest of technologies, one that the earth uses
when it puts vegetables and dinosaurs under pressure'' to form petroleum
deposits, Mr Woolsey said.
A $20 million facility at ConAgra's Butterball turkey plant in Carthage,
Missouri, is undergoing testing and expected to start using the technique by
the end of May, said Terry Adams, chief technology officer for Changing
World Technologies.
The plant ultimately will grind up, heat, pressurise, and process 200 tonnes
of leftover turkey innards, bones, feathers, fats and grease - enough to
produce 600 barrels of oil daily, officials say.
Mr Appel recently showed off the techniques at a pilot plant at the
Philadelphia Naval Business Centre. In one end went tyres, ground to
quarter-inch pieces by a giant industrial shredder. From the other end came
caramel-coloured liquid that resembles crude oil.
The plants can sell the oil to fuel blenders for use in home heating or
power-generating fuel. Refineries could process it as they do crude oil.
Utilities could burn it for power.
The process will digest just about anything: garbage, medical waste, hog
manure, old tires. Robert Brown, an engineering professor at the Centre for
Sustainable Environmental Technologies at Iowa State University, said
scientists have known for years how to use thermal depolymerisation to
convert waste into energy.
The problem, he said, is cost. Biological materials, like turkey byproducts,
contain water that must be removed before they can be turned into fuel.
Brown said biomatter also contains oxygen, which gives it less explosive
kick than fossil fuels.
''I'd be surprised if they can do it at a good price,'' he said.
Mr Appel acknowledged his process isn't competitive with crude oil. The
Missouri plant will need to spend $15 a barrel to turn turkey waste into
oil, compared with about $13 a barrel for small exploration and production
companies and $5 for a major oil company, he said.
Mr Appel said the cost will fall as more plants are built. He is also
pushing Congress for a clean-fuel subsidy to help it compete.
Mr Appel said 11 more projects are planned, including ones at a ConAgra
turkey plant in Longmont, Colorado, a poultry plant in Enterprise, Alabama.,
and an onion dehydration plant in Fernley, Nevada. The three projects
received nearly $10 million in grants from the Department of Energy.

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