ANIMALNET JULY 26, 1998 Rabbit hemorrhagic disease -- Australia: conclusions Bacterial Bug Tests Scores of Triathletes Epidemiology ALF-released mink bites 8-year-old girl Utah animal rights arson task force disbands Actress Betty White continues to distance herself from AR Conflicting Aims Leave Ban on Human Cloning in Limbo Hot summer hits bird business Monks Oppose Hog Farm Expansion Astronauts seek humane retirement for chimps Kim Basinger: Let my elephants go AnimalNet is produced by researchers at the Agri-Food isk Management and Communication Project at the University of Guelph, is edited by Wendy Powell (dpowell@uoguelph.ca) and Amanda Whitfield (awhitfie@uoguelph.ca), and is supported by the Ontario Cattlemen's Association, the U.S. National Pork Producers, U.S. National Food Processors Association, Pioneer Hi-Bred Limited (Canada), the U.S. National Cattlemens Beef Association, Canadian Animal Health Institute, The Rutgers University Food Safety Extension Program, National Cattlemans Beef Association, and the Agricultural Adaptation Council (CanAdapt Program). RABBIT HEMORRHAGIC DISEASE - AUSTRALIA: CONCLUSIONS July 24 /98 proMED I shall attempt to give you something of an update on some of the epidemiology of RHD as seen in Australia. I have recently performed analyses on data collected retrospectively on 245 release sites in NSW [New South Wales]. A paper arising from this work has recently been submitted to the Australian Veterinary Journal. The following paragraphs present the important findings and conclusions from this work. Results - For each week following cessation of rabbit breeding activity there was an 7% decline in the odds of an outbreak occurring. Low ambient temperatures were associated with outbreaks, with a decrease in the odds of disease falling by 13% for each 1C rise in mean monthly temperature in the month following release. The presence of high flea infestations (odds ratio 3.3) and moderate rainfall (25 to 50mm) in the month of release (odds ratio 27.4) were also associated with the occurrence of outbreaks. However, rainfall also was an effect modifier of temperature, whereby the sparing effect of high temperatures was apparently reduced in months in which the rainfall was over 50mm. Effects of lesser importance included the presence of RHD in the vicinity of the release site, which was associated with a mean population reduction 9% lower than those sites where RHD was not close by. However, the prior presence of RHDV on farm was found to be associated with an eight-fold increase in the odds of an outbreak occurring. The presence of cattle in the vicinity enhanced population declines by 12% over those properties without cattle. Increasing distance from the nearest water body was associated with a decrease in the odds of an outbreak occurring, such that for each 100 metre increment there was a 10% decline in the probability of disease occurrence. Conclusion - This is the first report finding a strong association between the presence of high flea numbers, breeding activity in rabbits and rainfall, and outbreaks of RHD. Although European rabbit flea numbers rise in concert with breeding activity in rabbits, the two factors may act independently. Fleas leaving dead viraemic rabbits in search of new hosts have great potential to increase viral transmission, and breeding activity may produce changes in physiology, behaviour and demography resulting in enhanced transmission. Low to mild environmental temperatures which enhance viral survival are also often associated with rabbit breeding activity in many areas. Moderate monthly rainfall may also stimulate breeding activity through the promotion of high quality pasture growth. Fly and mosquito activity, associated with proximity to cattle and water, suggests a minor role of these flying insects in local transmission. Firm evidence for persistence of the virus in a population following first introduction is provided by the greatly increased likelihood of outbreaks associated with the prior presence of RHDV in an area. The NSW tablelands areas suffer from a reduced likelihood of outbreaks and lower population declines than other parts of the state. Such effects may result from a less intense and more protracted breeding period in these cool, high rainfall areas where green feed is often available all year. An additional factor may be the presence of a non-virulent rabbit calicivirus, such as has been found in Europe, which may protect a proportion of the population from the virulent disease. The presence of such a virus in the moderate to high rainfall areas of Australia has been suspected following testing of sera from the Cooma and other districts. These sera, collected prior to the escape of RHDV from quarantine on Wardang Island, have demonstrated moderate caliciviral antibody levels in a proportion of the samples. Such pre-escape antibody levels have not been found in rabbits from semi-arid areas where high mortality rates (>95%) were seen following the initial RHD epidemic. In summary, it appears as though a significant proportion of the rabbit population must be reproducing (birth pulse) before a noticeable outbreak of RHD will occur. In high, reliable rainfall areas breeding activity may often occur at a low intensity and over too prolonged a period to allow development of outbreaks associated with high flea abundance. Efforts to artificially generate widespread and effective disease outbreaks are likely to be met with frustration unless necessary risk factors are present in the population or environment. Further, this association with breeding suggests that the virus and host have developed a stable relationship whereby outbreaks will occur only when some offspring are, by nature of age insusceptible, thereby facilitating survival of host populations and consequent viral persistence. If high levels of virus particles are only present in the blood during terminal stages of this acute disease then there will be little opportunity for mosquitoes, flies or fleas to transmit infection from live hosts. This is especially so if there is a high density threshold for infectious particles in the blood before successful transmission by biting insects can occur, as has been shown for myxomatosis. Thus, if most RHDV spread depends upon flea and fly transmission subsequent to host death, then there will also be continuing selection pressure for viral pathogenicity. Additional comments - The virus released in New Zealand was illegally derived from Australia, either a field isolate from a dead rabbit(s) or purified virus used for releases in Australia. New evidence involving positive PCR testing of lymphoepithelial tissues from serologically positive rabbits suggests that a carrier state exists in at least some recovered rabbits. It is conceivable that the stress associated with low temperatures and rainfall events may stimulate viral shedding and initiate outbreaks in populations in which sufficient other risk factors are present. Dr Ian Lugton Veterinary Epidemiologist Vertebrate Pest Research Unit NSW Agriculture Orange Agricultural Institute Orange 2800 Australia e-mail ian.lugton@agric.nsw.gov.au [What percentage of the European rabbit population was killed by this virus? Is the virus still spreading throughout Australia? Is there any evidence for increasing resistance against the virus? Any [scientific] evidence whatsoever that humans have been infected? - Mod.CHC] BACTERIAL BUG TESTS SCORES OF TRIATHLETES EPIDEMIOLOGY: HEALTH OFFICIALS FEAR HUNDREDS OF ATHLETES WHO COMPETED IN TWO MIDWEST EVENTS MAY HAVE BEEN SICKENED BY ONCE-RARE LEPTOSPIRA. July 25 /98 Los Angeles Times/ UPI WASHINGTON -- One-in-five athletes of more than 600 athletes contacted are experiencing symptoms such as muscle aches, fatigue, a pounding headache or the shakes, of illness from exposure -- apparently during the lake swim at the Ironhorse triathlon in Springfield, Ill -- to Leptospira. So far, 74 suspected cases of leptospirosis (LEHP'-toh-spah-ROH'- sihs), also known as swamp fever, have been identified. Christine, 33, a physical therapist from Holland, Pa. was quoted as saying, "I called a friend at work, and that's the last thing I remember" before waking up in a hospital with an intravenous line dripping into her arm. "He came to my apartment, found me lying on the floor drenched in sweat and carried me to the emergency room." Dr. John La Montagne, deputy director of the National Institute of Allergy and Infectious Diseases was quoted as saying, "We always seem to forget that infections are out there, that we are vulnerable and that they can cause us problems. Our only hope is to stay one step ahead of them." Dr. Jordan Tappero, the CDC medical epidemiologist who is heading the investigation was quoted as saying, "A lot of technology has gone into building these new surveillance systems, and we've got our state and local health departments thinking more about these emerging threats and about how people in this mobile society might in some way be linked." ALF-RELEASED MINK BITES 8 YEAR OLD GIRL July 24 /98 AMP News An eight year old girl was bitten by a mink that had been released from the laboratories of United Vaccines near Madison Wisconsin by members of the Animal Liberation Front over the Independence Day weekend. Molly Wright was eating breakfast on her patio with her mother when the mink jumped up and bit her. Fortunately, rabies tests came back negative and the girl will not have to endure rabies shots. Her mother told the Milwaukee Journal-Sentinel, "I'm sorry Molly got bitten and I'm glad it wasn't worse. But on the other hand, when we found out more about this group (ALF), the more upset I got because it was just totally responsible actions... Nothing good came out of this." In a perverse twist of logic, ALF press officer Katie Fedor put the blame for the girl's injury on United Vaccines. "United Vaccines is wholly responsible for that incident. If United Vaccines hadn't existed, this wouldn't have happened," she said. Of the 161 minks released in the break-in, about 100 have been recovered, as have 9 of 10 ferrets also released in the raid. About 15 minks were hit by cars and killed. UTAH ANIMAL RIGHTS ARSON TASK FORCE DISBANDS July 24 /98 AMP News The Salt Lake Tribune is reporting that an elite task force of local, county, and federal arson investigators that helped crack a rash of arson attacks by animal rights activists in the Salt Lake City area is disbanding. The Bureau of Alcohol, Tobacco and Firearms recently pulled its last agent from the Interagency Fire Investigation Unit, citing personnel constraints and the need to focus on the 2002 Olympics. Other agencies followed, in what one participant described as a domino effect. The task force will officially close August 10. "It was working really goodQeverybody that was involved can't believe it is going by the wayside because of manpower restraints," said Dennis Barker, a county fire captain who served as task force commander. "It is hurting all of us. None of us is happy about it." The task force was responsible for securing the arrests and convictions of several "straight-edge" animal rights activists who set fire to a leather store, mink farm and a McDonald's restaurant. ACTRESS BETTY WHITE CONTINUES TO DISTANCE HERSELF FROM AR July 25 /98 AMP News Actress and animal lover Betty White has told Modern Maturity magazine in no uncertain terms that she is not an animal rights activist. Here's the text of the relevant portion of her interview which appears in the July-August 1998 edition: MM: You support animal charities and are active in animal rightsQ WHITE: Not animal rightsQno, no, no. I correct people all the time. Animal welfare and well-being. MM: What's the difference? WHITE: Animal rightists are the demonstrators. I work for a healthier tomorrow for animals. MM: So you don't agree with the extremists or their methods? WHITE: Of course I don't. I'd just as soon not get into that because they have a whole following. I think they do more harm than good. They polarize a lot of people into saying "Oh, those crazy animal people" and paint us all with the same brush. CONFLICTING AIMS LEAVE BAN ON HUMAN CLONING IN LIMBO July 26 /98 Washington Post Caroline Daniel A08 Despite widespread concerns about the prospect of human cloning, if scientists wanted to try to clone a person today, according to this story, there arguably would be nothing to stop them. Several anti-cloning bills have been introduced in the U.S. Congress, but none has passed. And legal experts question the U.S. Food and Drug Administration's assertion that it has the authority to regulate human cloning, noting that the agency has not invoked that authority for other, similarly novel fertility treatments. John Freeman of Fish and Richardson, a Boston law firm that specializes in intellectual property was quoted as saying, "There are serious questions about whether the FDA can make its claim to be able to regulate cloning consistent with its [lack of] regulation of other reproductive techniques." The story adds that the possibility that someone could try to clone a human, and could succeed, became more likely last week when scientists in Hawaii announced that they had developed a new technique that had enabled them to clone dozens of adult laboratory mice. It was the first confirmed cloning of an adult mammal since Dolly the sheep was born in Scotland last year. The story adds that seven different legislative proposals emerged in the wake of the previous news. The Human Cloning Prohibition Act, introduced Feb. 3 and sponsored by Sens. Lott, Christopher S. Bond (R-Mo.) and Bill Frist (R-Tenn.), took the lead, with provisions that would outlaw the cloning of both embryos and adults. The bill was defeated. Meanwhile, Democrats offered a rival bill sponsored by Sens. Dianne Feinstein (D-Calif.) and Edward M. Kennedy (D-Mass.). This sought to ban the cloning of people, but not human embryos for research purposes. The bill was referred to the Senate Labor and Human Resources Committee, where it sits in quiet obscurity. Carl B. Feldbaum, president of the Biotechnology Industry Association, was quoted as saying, "We have not seen any indication of a bill. No new legislative draft is being circulated. Unless one is hastily put out at the last moment, we do not expect to see any legislative activity this session." Stepping into that legislative void, the FDA announced in February that anyone wanting to clone a person would have to apply for permission from that agency. But critics have questioned the legal basis of that claim. HOT SUMMER HITS BIRD BUSINESS July 25 /87 Sun Herald AP STARKVILLE -- Heat and humidity, some of broilers' worst enemies, have, according to this story, been harsh this summer causing Mississippi poultry industries to suffer significant bird losses. Mike McAlpin, president of the Mississippi Poultry Association was quoted as saying, "The loss of birds has not been catastrophic this summer. But they have been considerably higher than last summer." McAlpin added that heat and humidity affect bird weight and eating habits and that birds do not eat as well during high temperatures, causing them to gain weight slower. Tom Smith, poultry specialist at Mississippi State University's Extension Service was cited as saying that additional losses result when the birds are transported from the chicken houses to trucks where there is only air circulation. Jack Rogers, director of corporate services with B.C. Rogers Poultry, Inc., of Scott County was cited as saying that the heat this summer has made the company lose nearly 236,000 chickens. He said, according to this story, that other companies in the area had proportionately similar losses. He added that the company's growers are using several techniques and types of equipment to minimize the heat stress to the chickens. "Chickens are fed at night to avoid the heat of the day," Rogers said. "Growers also keep the birds supplied with cool fresh water with potassium and electrolyte supplements to keep them cooler." MONKS OPPOSE HOG FARM EXPANSION July 25 /98 Los Angeles Times AP PEOSTA, Iowa -- Monks at the New Melleray Abbey, according to this story, share a worry common in hog country: They are afraid that a new farm expansion will make their monastery smell to high heaven. Father Brendan Freeman, the abbot for the New Melleray Abbey near Dubuque was quoted as saying, "People come from all over the United States for quiet, prayer and reflection. We feel that's threatened. I think this is a good cause to stand up for." Joe Fitzgerald, the monastery's farm manager was quoted as saying, "You put a million gallons of hog manure together, it's not going to smell like fruit salad." ASTRONAUTS SEEK HUMANE RETIREMENT FOR CHIMPS July 25 /98 Electronic Telegraph Hugo Gurdon Eleven retired or current American astronauts are campaigning for a humane, research-free retirement for 33 former colleagues and their offspring - all of them chimpanzees. Buzz Aldrin, who walked on the Moon with Neil Armstrong, James Lovell, commander of the ill-fated Apollo 13 mission, was quoted as saying, "They and their descendants have served us in so many ways, initially as substitute humans in space research. Now is the time to repay this debt by giving these veterans the peaceful and permanent retirement they deserve." The National Aeronautics and Space Administration has invited bids to get rid of the chimp colony, instead of leasing the chimps to research scientists, as it has done in the past. But members of Congress, the story adds, and now the 11 astronauts, are concerned that the apes will go to the Coulston Foundation, a laboratory which has been using them since 1993 and which was charged in March with 24 violations of animal welfare law. The astronauts are backing a demand by the Centre for Captive Chimpanzee Care and the Doris Day Animal League that the chimps be allowed to retire "peacefully, humanely and permanently". KIM BASINGER: `LET MY ELEPHANTS GO!' Aug. 8 /98 Business Week Tammy Reiss Actress Kim Basinger, a spokeswoman for the Performing Animal Welfare Society (PAWS) is, according to this story, campaigning to keep circuses-- like Ringling Bros., Barnum & Bailey--from using elephants, which it claims are subject to abuse. She was quoted as telling Business Week, ``It's mind-boggling and scary to think what human beings are capable of doing with animals for a profit. We don't need elephants in circuses. We don't need any animals in circuses, and we don't need to call this entertainment.'' Barbara Pflughaupt, spokeswoman for Feld (owners of Ringling Bros., Branum and Bailey) was cited as saying, a circus isn't a circus without elephants, says, a privately held business with estimated 1997 revenues of $550 millionQand 40 elephants. ``Asian elephants are a part of us and of what we are. It would be counterproductive to do anything other than treat them well.'' 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